Human immune and gut microbial parameters associated with inter-individual variations in COVID-19 mRNA vaccine-induced immunity
M. Hirota, M. Tamai, S. Yukawa, N. Taira, M. M. Matthews, T. Toma, Y. Seto, M. Yoshida, S. Toguchi, M. Miyagi, T. Mori, H. Tomori, O. Tamai, M. Kina, E. Sakihara, , H. Ishikawa
The paper identifies baseline AP-1 gene expression and gut microbial fucose/rhamnose degradation as factors negatively correlated with BNT162b2 mRNA vaccine-induced T-cell responses.
bioRxiv · Aug 8, 2022 · PreprintImmunology