Author

H. Wakabayashi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Organism:human· 1

Frequent Co-Authors

D. Ermolenko· 2 shared C. Bao· 1 shared C. Warnasooriya· 1 shared D. Mathews· 1 shared I. Nykonchuk· 1 shared M. Zhu· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

D. Ermolenko

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2 papers

Recent·Most cited

Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation

C. Bao, M. Zhu, I. Nykonchuk, H. Wakabayashi, D. Mathews, D. Ermolenko

The paper shows that specific length and structure, not high thermodynamic stability, of mRNA stem-loops cause ribosome pauses by inhibiting tRNA binding and slowing translocation.

bioRxiv · Aug 16, 2021Biochemistry

Extending the spacing between the Shine-Dalgarno sequence and P-site codon reduces the rate of mRNA translocation

H. Wakabayashi, C. Warnasooriya, D. Ermolenko

The paper shows that increasing the spacer length between the Shine-Dalgarno sequence and P-site codon reduces mRNA translocation rate by 5-10 fold.

bioRxiv · Apr 16, 2020Biochemistry