Author

D. Ermolenko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:E. coli· 2 Organism:human· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Bao· 3 shared D. Mathews· 2 shared H. Wakabayashi· 2 shared A. A. Korostelev· 1 shared A. Das· 1 shared C. Ling· 1 shared C. Warnasooriya· 1 shared I. Nykonchuk· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBiochemistry

C. Bao

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Author profile →

5 papers

Recent·Most cited

Comparing FRET pairs that report on intersubunit rotation in bacterial ribosomes

A. Das, C. Bao, D. Ermolenko

The paper uses two FRET assays to study intersubunit rotation in bacterial ribosomes, finding spontaneous rotation occurs without EF-G and GTP hydrolysis.

bioRxiv · May 9, 2023Biochemistry

Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation

C. Bao, M. Zhu, I. Nykonchuk, H. Wakabayashi, D. Mathews, D. Ermolenko

The paper shows that specific length and structure, not high thermodynamic stability, of mRNA stem-loops cause ribosome pauses by inhibiting tRNA binding and slowing translocation.

bioRxiv · Aug 16, 2021Biochemistry

Making ends meet: new functions of mRNA secondary structure

D. Ermolenko, D. Mathews

This paper explores the biological implications of mRNA end proximity caused by secondary structure, suggesting roles in translation initiation and coupling of deadenylation to mRNA decay.

bioRxiv · Apr 29, 2020Biochemistry

Extending the spacing between the Shine-Dalgarno sequence and P-site codon reduces the rate of mRNA translocation

H. Wakabayashi, C. Warnasooriya, D. Ermolenko

The paper shows that increasing the spacer length between the Shine-Dalgarno sequence and P-site codon reduces mRNA translocation rate by 5-10 fold.

bioRxiv · Apr 16, 2020Biochemistry

mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding

C. Bao, S. Loerch, C. Ling, A. A. Korostelev, N. Grigorieff, D. Ermolenko

The paper investigates how mRNA stem-loops impede ribosome movement by hindering A-site tRNA binding and rotation during translation elongation.

bioRxiv · Feb 5, 2020Biochemistry