Author

I. Nykonchuk

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Biology Disciplines

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Biochemistry· 1

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Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:human· 1

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C. Bao· 1 shared D. Ermolenko· 1 shared D. Mathews· 1 shared H. Wakabayashi· 1 shared M. Zhu· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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1 shared paperBiochemistry

C. Bao

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1 paper

Recent·Most cited

Specific length and structure rather than high thermodynamic stability enable regulatory mRNA stem-loops to pause translation

C. Bao, M. Zhu, I. Nykonchuk, H. Wakabayashi, D. Mathews, D. Ermolenko

The paper shows that specific length and structure, not high thermodynamic stability, of mRNA stem-loops cause ribosome pauses by inhibiting tRNA binding and slowing translocation.

bioRxiv · Aug 16, 2021Biochemistry