PIEZO1-dependent erythrocyte dehydration as the mechanism for selection of an allele protecting from severe malaria.
J. Zimmerberg, S. E. Glushakova, L. Bezrukov, H. Waters, Y. Kegawa, P. S. Blank
The paper investigates how PIEZO1E756del variant causes RBC dehydration, inhibiting P. falciparum infection and protecting against severe malaria.
bioRxiv · Mar 31, 2022 · PreprintBiophysics