Clove Aqueous Extract Triggers a Multi-Organellar Stress Crisis through Lysosomal Destabilisation and Mitochondrial Hyperpolarisation to Suppress Patient-Derived Ovarian Cancer Cells
Yazid K. Ghanem, Hadeel Odwan, Musha Yang, Victoria Malone, Fawza Alenazi, Feras Abu Saadeh, S. Gray, Derek G. Doherty, Cara Martin, Sharon A. O'Toole, John J. O`Leary, Bashir M. Mohamed
This study shows that clove aqueous extract induces multi-organellar stress in ovarian cancer cells by disrupting lysosomes and mitochondria, leading to cell death.
bioRxiv · Feb 2, 2026 · PreprintCancer Biology