Linking Kinetochore Attachment to Checkpoint Control: The Role of Aurora B in BubR1 Acetylation
Siyoung Choi, Haemin Park, Sung-Soo Kim, Hyungmin Kim, Sanghyo Park, Hyunsook Lee
This paper identifies Aurora B-mediated phosphorylation and acetylation of BubR1 as critical for SAC signaling, linking kinetochore attachment to checkpoint activity and offering therapeutic targets for chromosome instability cancers.
Nucleic Acids Research · Dec 27, 2025Peer-reviewedCell Biology