Hyun‐Sook Lee

This paper identifies Aurora B-mediated phosphorylation and acetylation of BubR1 as critical for SAC signaling, linking kinetochore attachment to checkpoint activity and offering therapeutic targets for chromosome instability cancers.

The paper determines the structure of the insulin receptor complexed with a dimeric aptamer agonist, revealing how it induces full activation through specific conformational changes and intermolecular phosphorylation.

This paper shows that generative frame interpolation improves object tracking in time-lapse microscopy without requiring algorithm fine-tuning.

The paper investigates the mutational impact of ionizing radiation on normal cells and confirms these signatures in IR-induced cancers.