NAD+ treatment can increase directly the antioxidant capacity of rotenone-treated differentiated PC12 cells
Jie Zhang, Yunyi Hong, Wei Cao, Haibo Shi, Weihai Ying
This study shows NAD+ treatment increases antioxidant capacity in rotenone-treated PC12 cells by raising the GSH/GSSG ratio, suggesting a direct mechanism for its protective effects against oxidative stress.
bioRxiv · Dec 16, 2018 · PreprintCell Biology