Engineered Migrasomes: Harnessing Core Migrasome Machinery and Hypotonic Shock to Develop a Robust and Thermally Stable Vaccine Platform
Dongju Wang, Haifang Wang, Wei Wan, Zihui Zhu, Takami Sho, Yi Zheng, Xing Zhang, Longyu Dou, Qiang Ding, Li Yu, Zhihua Liu
This study engineers migrasome-like vesicles (eMigrasomes) using hypotonic shock to create a stable, thermally robust vaccine platform that elicits strong immune responses.
bioRxiv · Mar 13, 2024 · PreprintCell Biology