A Budding Yeast Model and Screen to Define the Functional Consequences of Oncogenic Histone Missense Mutations
Laramie D. Lemon, Sneha Kannan, Kim Wai Mo, Miranda Adams, Haley G. Choi, Alexander O. D. Gulka, Elise S. Withers, Hasset T. Nurelegne, Valeria Gomez, Reina E. Ambrocio, Rhea Tumminkatti, Richard Sean Lee, Morris Wan, Milo B. Fasken, Jennifer M. Spangle, Anita H. Corbett
The paper uses a budding yeast model to study the functional effects of oncogenic histone missense mutations and identifies suppressor genes involved in histone function and transcriptional regulation.
G3 Genes Genomes Genetics · May 14, 2022Peer-reviewedGenetics