Core Tri-fucosylation of Nematode N-glycans Requires Golgi α-mannosidase III Activity that Impacts Animal Growth and Behaviours
Jonatan Kendler, Florian Wӧls, Saurabh Thapliyal, Elsa Arcalís, Hanna Gabriel, Sascha Kubitschek, Daniel Malzl, Maria Regina Strobl, Dieter Palmberger, Thomas Luber, Carlo Unverzagt, Katharina Paschinger, Dominique A. Glauser, Iain B. H. Wilson, Shi Yan
This study identifies AMAN-3 as a Golgi α-mannosidase essential for tri-fucosylation of nematode N-glycans, which affects growth and behavior in C. elegans.
Journal of Biological Chemistry · Oct 30, 2024Peer-reviewedBiochemistry