Dominique A. Glauser

Starvation transforms signal encoding in C. elegans thermoresponsive neurons and suppresses heat avoidance via bidirectional glutamatergic and peptidergic signaling

Cohesin forms fountains at active enhancers in C. elegans

The paper identifies cohesin-dependent 3D chromatin structures called fountains around active enhancers in C. elegans, showing their role in repressing enhancer activity and linking genome architecture to behavior.

Antagonist actions of CMK-1/CaMKI and TAX-6/Calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli

This study identifies CMK-1 and TAX-6/CnA as antagonistic regulators of thermo-nociceptive adaptation in C. elegans, acting in distinct neurons to modulate noxious heat avoidance behaviors.

Core Tri-fucosylation of Nematode N-glycans Requires Golgi α-mannosidase III Activity that Impacts Animal Growth and Behaviours

This study identifies AMAN-3 as a Golgi α-mannosidase essential for tri-fucosylation of nematode N-glycans, which affects growth and behavior in C. elegans.

Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock

This study shows that Cdk5 activity, modulated by light, gates rapid circadian phase shifts by regulating calcium influx and signaling pathways in SCN neurons.

Multiple antagonist calcium-dependent mechanisms control CaM Kinase-1 subcellular localization in a C. elegans thermal nociceptor

The paper identifies multiple calcium-dependent mechanisms regulating CMK-1 subcellular localization in C. elegans thermal nociceptors, showing how phosphorylation and CaM binding interact to control nuclear entry and export.

Multisite gating in tonic sensory circuits integrates multimodal context to control persistent behavioral states

The paper shows how C. elegans integrates food and temperature inputs through multisite gating in sensory circuits to control persistent behavioral states.

Tissue-specific transcription footprinting using RNA PoI DamID (RAPID) in C. elegans

The paper introduces RAPID, a method to determine tissue-specific transcriptional footprints in C. elegans without cell sorting, and validates it by identifying novel transcriptional profiles in rare cell types.

Loss of CaMKI function disrupts salt aversive learning in C. elegans

The paper shows that CMK-1 in ASE neurons is essential for salt aversive learning in C. elegans by regulating calcium responses to salt.