Author

Saurabh Thapliyal

University of FribourgORCID 0000-0003-0363-4423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 4 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:Hi-C· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Dominique A. GlauseriD· 4 shared Anja Haemmerli· 1 shared Benjamin D. TowbiniD· 1 shared Bolaji N. Lüthi· 1 shared Carlo UnverzagtiD· 1 shared Daniel JostiD· 1 shared Daniel MalzliD· 1 shared Dario D’AsaroiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersNeuroscience

Dominique A. GlauserORCID

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4 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedOct 9, 2026

Starvation transforms signal encoding in C. elegans thermoresponsive neurons and suppresses heat avoidance via bidirectional glutamatergic and peptidergic signaling

Saurabh Thapliyal, Parvathi Sushama Gopinath, Dominique A. Glauser

DOI 10.7554/elife.108246.3

C. elegansexperimental assay

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GenomicsNature CommunicationsPeer-reviewedDec 11, 2025

Cohesin forms fountains at active enhancers in C. elegans

Bolaji N. Lüthi, Jennifer I. Semple, Anja Haemmerli…·Peter Meister

The paper identifies cohesin-dependent 3D chromatin structures called fountains around active enhancers in C. elegans, showing their role in repressing enhancer activity and linking genome architecture to behavior.

25 citationstop 3%

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BiochemistryJournal of Biological ChemistryPeer-reviewedOct 30, 2024

Core Tri-fucosylation of Nematode N-glycans Requires Golgi α-mannosidase III Activity that Impacts Animal Growth and Behaviours

Jonatan Kendler, Florian Wӧls, Saurabh Thapliyal…·Shi Yan

This study identifies AMAN-3 as a Golgi α-mannosidase essential for tri-fucosylation of nematode N-glycans, which affects growth and behavior in C. elegans.

7 citations

C. elegansproteomics

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NeurosciencebioRxivPreprintJul 14, 2022

Multisite gating in tonic sensory circuits integrates multimodal context to control persistent behavioral states

Saurabh Thapliyal, Isabel Beets, Dominique A. Glauser

The paper shows how C. elegans integrates food and temperature inputs through multisite gating in sensory circuits to control persistent behavioral states.

2 citations

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