NeurosciencebioRxivPreprint
Early postnatal CA3 hyperexcitability drives hippocampal development and epileptogenesis in SCN2A developmental and epileptic encephalopathy
Yana Reva, Katharina Ulrich, Xian Xin…·Dirk Isbrandt
This study shows that early postnatal CA3 hyperexcitability drives hippocampal development and epileptogenesis in SCN2A-DEE, suggesting it as a therapeutic target.
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