Peptide-based inhibitors of Tau aggregation as a potential therapeutic for Alzheimer's disease and other Tauopathies
Anthony Aggidis, Shreyasi Chatterjee, David J. Townsend, Nigel J. Fullwood, Eva Ruiz Ortega, Airi Tarutani, Masato Hasegawa, Hannah Lucas, Amritpal K. Mudher, David Allsop
This paper develops a peptide inhibitor, RI-AG03, that reduces Tau aggregation in vitro and improves Tauopathy symptoms in Drosophila.
bioRxiv · Jun 4, 2021 · PreprintNeuroscience