Author

Haoxiang Zhou

Manchester Academic Health Science Centre

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Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Abigail Bennington· 1 shared Anna van der Zwaluw· 1 shared Basudha BasuiD· 1 shared Colin A. JohnsoniD· 1 shared Dapeng WangiD· 1 shared Kashish Jain· 1 shared Kathryn E. HentgesiD· 1 shared Louise A. StepheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperDevelopmental Biology

Abigail Bennington

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1 paper

Recent·Most cited

Prpf8N1531S homozygous mutant mouse embryos have multiple defects in cardiac development and show aberrant splicing of the cardiac transcription factor Tead1

Wasay Mohiuddin Shaikh Qureshi, Haoxiang Zhou, Abigail Bennington, Nouf J. Althali, Anna van der Zwaluw, Michael Boylan, Louise A. Stephen, Kashish Jain, Basudha Basu, Dapeng Wang, Colin A. Johnson, Kathryn E. Hentges

This study identifies a critical role for Prpf8 in cardiac development through aberrant splicing of Tead1 and disrupted Notch signaling in Prpf8N1531S homozygous mutant mice.

bioRxiv · Apr 21, 2026 · PreprintDevelopmental Biology