The mechanosensitive protein Zyxin influences Hippo signalling and tissue growth via adherens junctions and basal spot junctions in Drosophila
Harmanjeet Singh, Elliot Brooks, Kyoko Jinnai, Shu Kondo, Samuel A. Manning, Benjamin Kroeger, Kieran F. Harvey
This study shows Zyxin and Ajuba limit Hippo signaling and promote Drosophila tissue growth by regulating junctions and Warts kinase activity.
bioRxiv · Feb 14, 2026 · PreprintDevelopmental Biology