BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides
Harry R. King, Mark Bycroft, Thanh Nguyen…·Katerina Artavanis‐Tsakonas
This study identifies chemically constrained peptides that inhibit PfUCHL3, a critical deubiquitinating enzyme in Plasmodium falciparum, by blocking substrate binding rather than active site interaction.
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