BiochemistryJournal of the American Chemical SocietyPeer-reviewed
Aminoacyl-tRNA specificity of a ligase catalyzing non-ribosomal peptide extension
Dinh Thanh Nguyen, Josseline S. Ramos‐Figueroa, Alexander A. Vinogradov…·Douglas A. Mitchell
This study investigates the substrate specificity of the PEARL BhaBCAla, showing it can use non-cognate amino acids and tRNAs for peptide extension, with efficiency depending on both amino acid and tRNA features.
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