Author

Harshavardhan Madhan

Indian Institute of Technology Madras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

Athi N. NaganathaniD· 2 shared David De SanchoiD· 1 shared Satoshi TakahashiiD· 1 shared Shilpi Laha· 1 shared Yuji ItohiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Athi N. NaganathanORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Hashi: Bridging Statistical Model Derived 1D Microstate Encodings and Protein 3D Structural Ensembles

Harshavardhan Madhan, Athi N. Naganathan

Hashi generates realistic protein structural ensembles from WSME model outputs, enabling rapid analysis of conformational states and functional insights.

bioRxiv · Aug 31, 2026 · PreprintBiophysics

Switching Functional DNA-Binding Modes by Tuning Protein Order-Disorder Equilibria

Shilpi Laha, Harshavardhan Madhan, Yuji Itoh, David De Sancho, Satoshi Takahashi, Athi N. Naganathan

This study shows how phosphorylation tuning affects Nhp6A's conformational equilibria and DNA binding modes, revealing a conserved mechanism for chromatin regulation.

bioRxiv · Aug 18, 2026 · PreprintBiophysics