Author

Yuji Itoh

Tohoku UniversityORCID 0000-0002-6699-8665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:virus· 2 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1 Organism:yeast· 1

Frequent Co-Authors

Satoshi TakahashiiD· 3 shared Athi N. NaganathaniD· 2 shared Shilpi Laha· 2 shared David De SanchoiD· 1 shared Fumi NagatsugiiD· 1 shared Harshavardhan Madhan· 1 shared Hiroto TakahashiiD· 1 shared Hiroyuki OikawaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBiophysics

Satoshi TakahashiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Switching Functional DNA-Binding Modes by Tuning Protein Order-Disorder Equilibria

Shilpi Laha, Harshavardhan Madhan, Yuji Itoh, David De Sancho, Satoshi Takahashi, Athi N. Naganathan

This study shows how phosphorylation tuning affects Nhp6A's conformational equilibria and DNA binding modes, revealing a conserved mechanism for chromatin regulation.

bioRxiv · Aug 18, 2026 · PreprintBiophysics

A Structural Domain in the genomic RNA of SARS-CoV-2 Folds into a Compact Granular Structure without the N protein: A Single-Molecule Fluorescence Spectroscopic Investigation

Takahiro Kimura, Takuya Katayama, Shion Ishikawa, Shrutarshi Mitra, Yuuhei Yamano, Kazumitsu Onizuka, Fumi Nagatsugi, Shilpi Laha, Athi N. Naganathan, Yuji Itoh, Satoshi Takahashi

This study shows a specific SARS-CoV-2 genomic RNA region forms compact granular structures autonomously without the N protein, and the N protein melts these structures, suggesting it acts as an RNA chaperone.

bioRxiv · May 15, 2026 · PreprintBiophysics

A single dimer of the SARS-CoV-2 N protein can associate with multiple fragments of single-stranded and stem-loop RNAs

Naoya Kaneda, Leo Suzuki, Shun Endo, Syamil Muharror Ahsanul Husna, Shion Ishikawa, Hiroto Takahashi, Hiroyuki Oikawa, Yuji Itoh, Satoshi Takahashi

This study investigates how SARS-CoV-2 N protein interacts with different RNA structures, showing it can bind multiple RNA fragments per dimer and may help fold viral RNA into RNP granules.

bioRxiv · Jan 23, 2025 · PreprintBiophysics