Environmental Enrichment Attenuates Fentanyl-Seeking Behavior and Protects Against Stress-Induced Reinstatement in Both Male and Female Rats
Jessica A. Higginbotham, Joanna J. Dearman, Mateo Pujol, Rachel Teich, Hasan Maqbool, José A. Morón
This study shows that object-based environmental enrichment reduces fentanyl intake and stress-induced relapse in rats, suggesting it could be a scalable intervention for opioid use and relapse prevention.
eNeuro · Apr 1, 2026Peer-reviewedAnimal Behavior & Cognition