Comprehensive characterization of single cell full-length isoforms in human and mouse with long-read sequencing
Luyi Tian, Jafar S. Jabbari, Rachel Thijssen…·Matthew E. Ritchie
The paper develops FLT-seq and FLAMES to characterize full-length isoforms in single cells of human and mouse, identifying thousands of unannotated isoforms and linking them to functional modules and drug resistance mutations.