Validation of DoriVac (DNA origami vaccine) efficacy in a metastatic melanoma model
Anjali Rajwar, Hawa Dembele, Amanda R. Graveline, Andyna Vernet, Melinda Sanchez, Sarai Bardales, Ick Chan Kwon, Ju Hee Ryu, William M. Shih, Yang C. Zeng
This study validates DoriVac, a DNA origami vaccine, as an effective treatment for metastatic melanoma in mouse models, showing reduced tumor nodules and enhanced immune activation when combined with PD-L1 blockade.
ACS Applied Materials & Interfaces · Apr 29, 2026Peer-reviewedSynthetic Biology