Sex-specific and age-related progression of auditory neurophysiological deficits in the Cln3 mouse model of Batten disease
Yanya Ding, Jingyu Feng, Viollandi Prifti, Grace A. Rico, Alexander G. Solorzano, Hayley E. Chang, Edward G. Freedman, John J. Foxe, Kuan Hong Wang
This study investigates sex-specific and age-related auditory neurophysiological deficits in Cln3-/- mice using MMN paradigms, revealing central auditory processing issues that mirror human CLN3 disease findings.
Journal of Neurodevelopmental Disorders · Nov 6, 2025Peer-reviewedNeuroscience