Psychedelic-mediated Reversal of General Anesthesia and Restoration of Brain Dynamics in Rat
Emma R. Huels, Nicholas Kolbman, Christopher W. Fields, Amanda G. Nelson, Hazel Jackson, Tiecheng Liu, George A. Mashour, Dinesh Pal
This study shows that DOI, a serotonergic psychedelic, can reverse general anesthesia and restore brain dynamics in rats, as evidenced by behavioral arousal and recovery of functional connectivity.
bioRxiv · Jan 22, 2025 · PreprintNeuroscience