Deficiency of complement component C1Q prevents cerebrovascular damage and white matter loss in a mouse model of chronic obesity
Leah C. Graham, Heidi E. Kocalis, Ileana Soto, Gareth R. Howell
This study shows that deficiency of C1QA prevents cerebrovascular damage and white matter loss in obese mice, suggesting a role for the complement cascade in obesity-induced brain pathology.
eNeuro · Apr 9, 2020Peer-reviewedNeuroscience