Matrix stiffness-induced IKBKE and MAPK8 signaling drives a phenotypic switch from DCIS to invasive breast cancer
Feifei Yan, Sara Göransson, Helene Olofsson, Christos Vogiatzakis, Anagha Acharekar, Staffan Strömblad
The paper identifies matrix stiffness-induced IKBKE and MAPK8 signaling as drivers of the phenotypic switch from DCIS to invasive breast cancer and suggests potential therapeutic inhibitors.
Cell Communication and Signaling · Jun 4, 2025Peer-reviewedCancer Biology