Cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to support fuel preference for fatty acids
Chul‐Hong Park, Minsung Park, Miranda E. Kelly, Helia Cheng, Sang Ryeul Lee, Cholsoon Jang, Ji Suk Chang
This study identifies how cold-inducible GOT1 activates the malate-aspartate shuttle in brown adipose tissue to promote fatty acid oxidation over glucose.
Cell Reports · Jun 19, 2025Peer-reviewedCell Biology