Environmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer
Meadow E. Parrish, Meloryn Seraj, Helia Nikoueian, Nicole C. Traugh, Andrew Chen, Piyush B. Gupta, Stefano Monti, Charlotte Kuperwasser
This study shows that environmental chemical mixtures disrupt mammary development and induce epigenetic changes linked to breast cancer, particularly invasive lobular carcinoma.
bioRxiv · Apr 3, 2026 · PreprintCancer Biology