Author

Hemant Joshi

Tsinghua University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Babak JavidiD· 2 shared Gang Liu· 1 shared Hong-Wei Su· 1 shared I.D. YoungiD· 1 shared James S. FraseriD· 1 shared Jia-Yao HongiD· 1 shared Jie WuiD· 1 shared Miaomiao Pan· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Babak JavidORCID

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2 papers

Recent·Most cited

A small molecule increases mycobacterial translation fidelity without a fitness cost by targeting ribosomal protein S5

Jie Wu, Swarnava Chaudhuri, Sarah C. Feid, Hemant Joshi, Miaomiao Pan, Qingwen Kawaji, Gang Liu, Babak Javid

This paper identifies a small molecule that enhances translational fidelity in mycobacteria without reducing translation speed, targeting ribosomal protein S5 to combat antibiotic tolerance.

mBio · Oct 2, 2026Peer-reviewedMicrobiology

Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA

Zhuo Bi, Yuxiang Chen, I.D. Young, Mohamad T Dandan, Hemant Joshi, Hong-Wei Su, Yuemeng Chen, Jia-Yao Hong, James S. Fraser, Babak Javid

The paper shows that GidB-mediated 16S rRNA methylation in mycobacteria enhances discrimination of mischarged tRNAs, improving translational fidelity in high mistranslation environments.

bioRxiv · Mar 2, 2021Molecular Biology