Author

Gang Liu

Tsinghua University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Microbiology· 3 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Babak JavidiD· 1 shared Bing Hu· 1 shared Chunxia Ao· 1 shared Feng ZhouiD· 1 shared Gilberto E. FloresiD· 1 shared He-ying Chen· 1 shared Hemant Joshi· 1 shared Hong-long Wu· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperMicrobiology

Babak JavidORCID

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Author profile →

5 papers

Recent·Most cited

A small molecule increases mycobacterial translation fidelity without a fitness cost by targeting ribosomal protein S5

Jie Wu, Swarnava Chaudhuri, Sarah C. Feid, Hemant Joshi, Miaomiao Pan, Qingwen Kawaji, Gang Liu, Babak Javid

This paper identifies a small molecule that enhances translational fidelity in mycobacteria without reducing translation speed, targeting ribosomal protein S5 to combat antibiotic tolerance.

mBio · Oct 2, 2026Peer-reviewedMicrobiology

OGG1-Binding to Oxidized Guanine Base in Viral DNA Overcomes Epstein-Barr Virus Latency

Wenjing Hao, Xiaoqi Wang, Jiabo Li, Gang Liu, Lang Pan, Xueqing Ba, I. Boldogh, Ziyuan Duan

This study shows that OGG1 binding to oxidized guanine in EBV DNA promotes reactivation by activating lytic genes, suggesting OGG1 as a therapeutic target.

bioRxiv · Jun 6, 2026 · PreprintMicrobiology

ZMS-6659, a selective Polθ helicase inhibitor, demonstrates anti-tumor activity as monotherapy and synergy effect with PARP inhibitors and topoisomerase inhibitors

Lei Jiang, Jiajia Li, Lu Liu, Mengying Li, Wenjing Li, Zhen Li, Shuo Qian, Mingyue Shi, Jing Dai, Chunxia Ao, Ying Qu, Zhengtao Li, Li Zhou, Yang Chen, Xiyuan Wang, , Liting Xue

ZMS-6659, a Polθ helicase inhibitor, shows anti-tumor activity as monotherapy and synergizes with PARP inhibitors and topoisomerase inhibitors in HR-deficient and HR-proficient models.

bioRxiv · Apr 19, 2025 · PreprintCancer Biology

Clustering of the structures by using \"snakes-and-dragons\" approach, or correlation matrix as a signal

Victor P. Andreev, Gang Liu, Jarcy Zee, Lisa L. Henn, Gilberto E. Flores, Robert M. Merion

The paper introduces a new method for clustering correlation matrices called 'snakes-and-dragons' and applies it to neuroscience, human microbiome, and macroeconomics data.

PLoS ONE · Oct 10, 2019Peer-reviewedBioinformatics

Next-Generation Sequencing Could be a Promising Diagnostic Approach for Pathogen Detection: Pathogenic Analysis of Pediatric Bacterial Meningitis by Next-Generation Sequencing Technology Directly from Cerebrospinal Fluid Specimens

Ling-yun Guo, Yong-jun Li, Lin-lin Liu, Hong-long Wu, Jia-li Zhou, Ye Zhang, Wen-ya Feng, Liang Zhu, Bing Hu, Hui-li Hu, Tian-ming Chen, Xin Guo, He-ying Chen, Yong-hong Yang, Gang Liu

This study uses next-generation sequencing on CSF samples to identify pathogens in pediatric bacterial meningitis cases, finding it more effective than traditional methods.

bioRxiv · Jun 6, 2018 · PreprintMicrobiology