Author

Heng-Ai Chang

The Royal Victorian Eye & Ear Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alex William HewittiD· 1 shared Alicia A. BrunetiD· 1 shared Anai Gonzalez-CorderoiD· 1 shared Chi D. LuuiD· 1 shared Deborah AubiniD· 1 shared Fan Li· 1 shared Guei‐Sheung LiuiD· 1 shared Jun YangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Alex William HewittORCID

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1 paper

Recent·Most cited

Engineering single-AAV CRISPR-Cas13 RNA base editors for treatment of inherited retinal diseases

Satheesh Kumar, Heng-Ai Chang, Deborah Aubin, Yi-Wen Hsiao, Alicia A. Brunet, Jun Yang, Liuhui Huang, Chi D. Luu, Alex William Hewitt, Fan Li, Lewis E Fry, Lívia S. Carvalho, Anai Gonzalez-Cordero, Guei‐Sheung Liu

This paper develops an RNA base editor using CRISPR-Cas13 and ADAR2DD to correct mutations in inherited retinal diseases, showing up to 60% editing efficiency in vitro and partial rescue in mouse models.

bioRxiv · Aug 6, 2025 · PreprintBioengineering