Author

Henning Schurse

Universitätsklinikum Aachen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea Küster· 2 shared Gerhard Müller‐NeweniD· 2 shared Madeline J. CaduciD· 1 shared Marcelo A. S. ToledoiD· 1 shared Merith Borgen-Möller· 1 shared Sabrina Ernst· 1 shared Stefan DüsterhöftiD· 1 shared Steffen KoschmiederiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

Andrea Küster

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2 papers

Recent·Most cited

Unexpected functional role of the transactivation domain for nuclear import of STAT5

Sabrina Ernst, Merith Borgen-Möller, Andrea Küster, Henning Schurse, Gerhard Müller‐Newen

The paper identifies a role for the transactivation domain in STAT5 nuclear import, showing that a 12-amino-acid stretch and specific residues are essential for this process.

Communications Biology · Sep 26, 2026Peer-reviewedCell Biology

The V617F mutation in JAK2 renders myeloid cells more sensitive to IL-6-mediated gp130 signaling

Henning Schurse, Marcelo A. S. Toledo, Andrea Küster, Steffen Koschmieder, Madeline J. Caduc, Stefan Düsterhöft, Gerhard Müller‐Newen

This study shows that the JAK2 V617F mutation enhances IL-6 sensitivity by promoting gp130 dimerization and expression in myeloid cells, contributing to chronic inflammation in MPN.

bioRxiv · Oct 10, 2025 · PreprintCancer Biology