Intraepithelial lymphocytes exhibit selective immunity to intestinal pathogens
Amanpreet Singh Chawla, Olivia J. James, Purbasha Bhattacharya, Dina Dikovskaya, Suzanne H. Hodge, Maud Vandereyken, Lee Robinson, Henry M McSorley, Mattie Christine Pawlowic, Mahima Swamy
This study shows that intraepithelial lymphocytes (IELs) are critical for resisting specific intestinal pathogens but not for maintaining intestinal homeostasis or other infections.
bioRxiv · May 14, 2025 · PreprintImmunology