Suzanne H. Hodge

This paper describes the structure of HpBARI2, a helminth-derived protein that trimerises to selectively inhibit membrane-bound ST2 receptor signaling by blocking IL-33 binding and preventing co-receptor recruitment.

This paper investigates the role of mast cell ST2 in Heligmosomoides polygyrus bakeri infection using transcriptomic and proteomic analysis, finding minimal impact on infection outcomes.

This study shows that intraepithelial lymphocytes (IELs) are critical for resisting specific intestinal pathogens but not for maintaining intestinal homeostasis or other infections.

This paper shows that vaccinating against helminth IL-33-modulators can protect against infection by reversing immunosuppression and enhancing Th2 immunity.