Author

Hesther de Ruiter

Royal Netherlands Academy of Arts and Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Anneline S.J.M. te RieleiD· 1 shared B. M. T. Burgering· 1 shared Daphne van den Berg· 1 shared Eirini KyriakopoulouiD· 1 shared Eva van RooijiD· 1 shared Hoyee TsuiiD· 1 shared Ilaria Perini· 1 shared Ilse R. KeltersiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Anneline S.J.M. te RieleORCID

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1 paper

Recent·Most cited

PKP2 orchestrates OXPHOS expression in cardiomyocytes via a PGC1α-dependent mechanism

Su Ji Han, Daphne van den Berg, Hesther de Ruiter, Hoyee Tsui, Eirini Kyriakopoulou, Tim Koopmans, Ilaria Perini, Jantine Monshouwer‐Kloots, Sebastiaan J. van Kampen, Anneline S.J.M. te Riele, Ilse R. Kelters, Monica Gianoli, B. M. T. Burgering, Eva van Rooij

This study identifies reduced oxidative phosphorylation (OXPHOS) in PKP2 mutant cardiomyocytes due to lower PPARGC1A expression, suggesting PPARGC1A modulation as a potential therapeutic target for arrhythmogenic cardiomyopathy.

Cardiovascular Research · Jul 6, 2026Peer-reviewedMolecular Biology