Author

Sebastiaan J. van Kampen

Leiden University Medical CenterORCID 0000-0002-4146-8481Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Albert Blanch-AsensioiD· 1 shared Anneline S.J.M. te RieleiD· 1 shared B. M. T. Burgering· 1 shared Babet van der VaartiD· 1 shared Christian M.A.H. FreundiD· 1 shared Christine L. MummeryiD· 1 shared Daphne van den Berg· 1 shared Eirini KyriakopoulouiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Albert Blanch-AsensioORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PKP2 orchestrates OXPHOS expression in cardiomyocytes via a PGC1α-dependent mechanism

Su Ji Han, Daphne van den Berg, Hesther de Ruiter, Hoyee Tsui, Eirini Kyriakopoulou, Tim Koopmans, Ilaria Perini, Jantine Monshouwer‐Kloots, Sebastiaan J. van Kampen, Anneline S.J.M. te Riele, Ilse R. Kelters, Monica Gianoli, B. M. T. Burgering, Eva van Rooij

This study identifies reduced oxidative phosphorylation (OXPHOS) in PKP2 mutant cardiomyocytes due to lower PPARGC1A expression, suggesting PPARGC1A modulation as a potential therapeutic target for arrhythmogenic cardiomyopathy.

Cardiovascular Research · Jul 6, 2026Peer-reviewedMolecular Biology

Controlled Induction of ALK1 in ACVRL1-null hiPSC-derived Endothelial Cells Provides Insight into Organ-Restricted AVMs in HHT

Sebastiaan J. van Kampen, Albert Blanch-Asensio, James Gallant, Babet van der Vaart, Christian M.A.H. Freund, Richard P. Davis, Christine L. Mummery, Valeria V. Orlova

The paper develops a tunable in vitro model to study ALK1's role in HHT by inducing ALK1 in ACVRL1-null hiPSC-derived endothelial cells, showing threshold-dependent restoration of endothelial function.

bioRxiv · Aug 22, 2025 · PreprintMolecular Biology