Cystatin C is glucocorticoid-responsive, directs recruitment of Trem2+ macrophages and predicts failure of cancer immunotherapy
Sam O Kleeman, Tuba Mansoor Thakir, Breanna R. Demestichas, Nicholas Mourikis, Dominik Loiero, Miriam Ferrer, Sean Bankier, Yosef Joseph Rene Amel Riazat‐Kesh, Hassal Lee, Dimitrios Chantzichristos, Claire Regan, Jonathan B. Preall, Sarthak Sinha, Nicole Rosin, Bryan G. Yipp, , et al
This study identifies Cystatin C as a glucocorticoid-responsive factor that recruits Trem2+ macrophages and predicts immunotherapy failure in cancer.
Cell Genomics · Aug 1, 2023Peer-reviewedGenetic & Genomic Medicine