Author

Dimitrios Chantzichristos

Sahlgrenska University HospitalORCID 0000-0002-1660-1973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Gudmundur JohannssoniD· 2 shared Adam StevensiD· 1 shared Anja MeyeriD· 1 shared Antoine DufouriD· 1 shared Arno RuusaleppiD· 1 shared Breanna R. DemestichasiD· 1 shared Brian Robert WalkeriD· 1 shared Bryan G. YippiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSystems Biology

Gudmundur JohannssonORCID

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2 papers

Recent·Most cited

Higher-Order Organization Links Circulating Metabolites to Glucocorticoid Action in Human Adipose Tissue

Kate Bennett, Dimitrios Chantzichristos, Terence Garner, Per‐Anders Jansson, Anja Meyer, Eleanor A. Doman, Johanna McQueen, Per‐Arne Svensson, Óskar Ragnarsson, Gudmundur Johannsson, Adam Stevens

The paper investigates how glucocorticoid exposure affects adipose metabolism and identifies a circulating biomarker, the phenylalanine/kynurenine ratio, that reflects GC state and has potential for personalized therapy.

bioRxiv · Oct 9, 2026 · PreprintSystems Biology

Cystatin C is glucocorticoid-responsive, directs recruitment of Trem2+ macrophages and predicts failure of cancer immunotherapy

Sam O Kleeman, Tuba Mansoor Thakir, Breanna R. Demestichas, Nicholas Mourikis, Dominik Loiero, Miriam Ferrer, Sean Bankier, Yosef Joseph Rene Amel Riazat‐Kesh, Hassal Lee, Dimitrios Chantzichristos, Claire Regan, Jonathan B. Preall, Sarthak Sinha, Nicole Rosin, Bryan G. Yipp, , et al

This study identifies Cystatin C as a glucocorticoid-responsive factor that recruits Trem2+ macrophages and predicts immunotherapy failure in cancer.

Cell Genomics · Aug 1, 2023Peer-reviewedGenetic & Genomic Medicine