Author

Hi-jea Cha

Goethe University Frankfurt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Achilleas S FrangakisiD· 1 shared Attilio Vittorio VargiuiD· 1 shared Clara BörnseniD· 1 shared Eiki YamashitaiD· 1 shared Hui ZengiD· 1 shared Inga M. Spannaus· 1 shared Kay DiederichsiD· 1 shared Klaas Martinus PosiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Achilleas S FrangakisORCID

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1 paper

Recent·Most cited

Conformational plasticity across phylogenetic clusters of RND multidrug efflux pumps and its impact on substrate specificity

Mariya Lazarova, Thomas Eicher, Clara Börnsen, Hui Zeng, Mohd Athar, Ui Okada, Eiki Yamashita, Inga M. Spannaus, Max Borgosch, Hi-jea Cha, Attilio Vittorio Vargiu, Satoshi Murakami, Kay Diederichs, Achilleas S Frangakis, Klaas Martinus Pos

This study shows that a single conserved residue transfer between RND efflux pump clusters alters drug resistance and conformational dynamics.

Nature Communications · Nov 26, 2025Peer-reviewedBiochemistry