Author

Achilleas S Frangakis

Goethe University FrankfurtORCID 0000-0002-4364-6202Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Clara BörnseniD· 2 shared Klaas Martinus PosiD· 2 shared Sina MangeriD· 2 shared Ashwin BalakrishnaniD· 1 shared Attilio Vittorio VargiuiD· 1 shared C Thiel· 1 shared Daniela Bublak· 1 shared Eiki YamashitaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Clara BörnsenORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 3, 2026

Cell-envelope conduits enable transfer of megabase-sized double-stranded DNA between cells of the nosocomial pathogen Acinetobacter baumannii

Sina Manger, Clara Börnsen, Sara Garcia Torres…·Achilleas S Frangakis

The paper identifies cell-envelope conduits in Acinetobacter baumannii that enable direct transfer of large chromosomal DNA segments between cells.

DOI 10.64898/2026.09.02.748809

Arabidopsisexperimental assay

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BiochemistryNature CommunicationsPeer-reviewedNov 26, 2025

Conformational plasticity across phylogenetic clusters of RND multidrug efflux pumps and its impact on substrate specificity

Mariya Lazarova, Thomas Eicher, Clara Börnsen…·Klaas Martinus Pos

This study shows that a single conserved residue transfer between RND efflux pump clusters alters drug resistance and conformational dynamics.

12 citations

E. coliprotein structure

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Molecular BiologybioRxivPreprintOct 24, 2023

How does Mycoplasma pneumoniae steal lipids from its host membranes?

Sina Manger, Serena M. Arghittu, Lasse Sprankel…·Achilleas S Frangakis

This study identifies how Mycoplasma pneumoniae uses the protein P116 to transport lipids between membranes without ATP, revealing a simplified lipid uptake mechanism.

DOI 10.1101/2023.10.24.563710

bacteria (other)statistical model

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