Single-cell quantification of senescence burden reveals cell type-specific ageing dynamics across organs
Ulysse Cherqui, Ilanit Sopher, Hagay Akiva, O. Menahem, E. Kopitman, Ronnie Blecher‐Gonen, Hadas Keren‐Shaul, Noa Rachmian, Avi Mayo, Uri Alon, Hilah Gal, Valery Krizhanovsky
This study quantifies senescence burden at the single-cell level across tissues in mice and human PBMCs, revealing tissue-specific ageing dynamics and senescence marker heterogeneity.
bioRxiv · Nov 14, 2025 · PreprintCell Biology