Author

Himani Aligireddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ashley N. Reeb· 1 shared Dhruva D. DhavaleiD· 1 shared Jan BieschkeiD· 1 shared Niraja Kedia· 1 shared Paul T. KotzbaueriD· 1 shared Rachel L. FrenchiD· 1 shared Yuna M. AyalaiD· 1 shared Zachary R. Grese· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Ashley N. Reeb

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1 paper

Recent·Most cited

TDP-43 oligomers detected as initial intermediate species during aggregate formation

Rachel L. French, Ashley N. Reeb, Himani Aligireddy, Niraja Kedia, Dhruva D. Dhavale, Zachary R. Grese, Paul T. Kotzbauer, Jan Bieschke, Yuna M. Ayala

This study identifies TDP-43 oligomers as early intermediates in aggregation, showing ALS-linked mutations accelerate this process and enhance aggregate propagation.

bioRxiv · Dec 17, 2018 · PreprintBiochemistry