NeuroscienceBiological PsychiatryPeer-reviewed
Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response
Himanshu K. Mishra, Noelle M. Ying, Angelica Luis…·Michael J. McCarthy
This study shows that bipolar disorder patient-derived neurons exhibit circadian rhythm abnormalities, with lithium non-responders showing more severe deficits that can be partially reversed by temperature entrainment.