Author

Hon-Chi Lee

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:electrophysiology· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1 Research Focus:variant effect prediction· 1 Organism:zebrafish· 1

Frequent Co-Authors

Tong LuiD· 2 shared Dao Wen WangiD· 1 shared Dao Wu WangiD· 1 shared David J. TesteriD· 1 shared Fernando Berton ZanchiiD· 1 shared Hector R. VillarragaiD· 1 shared James R. CerhaniD· 1 shared Jingchun YangiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

Tong LuORCID

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Author profile →

2 papers

Recent·Most cited

Functional Evaluation of TRPC6 Missense Variants in Cancer Patients via Molecular Docking Analysis Compared with Patch Clamp Electrophysiology

Ying Wu, Xiaojing Sun, Joseph S. Reddy, Pooja Prem Advani, Nicholas James Boddicker, James R. Cerhan, Hector R. Villarraga, Samuel J. Asirvatham, Ru-Xing Wang, Hon-Chi Lee, Nadine Norton, Fernando Berton Zanchi, Tong Lu

This study evaluates TRPC6 missense variants in cancer patients using molecular docking and patch clamp electrophysiology to predict functional impact and guide clinical decisions.

Journal of Biological Chemistry · May 6, 2026Peer-reviewedPhysiology

SORBS2 is a susceptibility gene to arrhythmogenic right ventricular cardiomyopathy

Yonghe Ding, Jingchun Yang, Peng Chen, Tong Lü, Kunli Jiao, David J. Tester, Kai Jiang, Michael John Ackerman, Yi‐Gang Li, Dao Wu Wang, Dao Wen Wang, Hon-Chi Lee, Xiaolei Xu

The paper identifies SORBS2 as a new susceptibility gene for arrhythmogenic right ventricular cardiomyopathy (ARVC) using zebrafish and mouse models and human patient sequencing.

bioRxiv · Aug 5, 2019 · PreprintGenetics