MetScore and classical-basal subtype intersect to define chemotherapy response and tumor microenvironment architecture in pancreatic ductal adenocarcinoma
Raymond E. Preston, Hongyu Huang, Margaret A Hall, Udhayvir Singh Grewal, Kawther Abdilleh, Sudheer Doss, Richard A. Moffitt, Olatunji Boladale Alese, Gregory B. Lesinski, Jesse Stone Handler
The paper integrates MetScore with classical-basal subtype to better explain PDAC metastasis, prognosis, treatment response, and tumor microenvironment than a single-axis model.
bioRxiv · Sep 17, 2026 · PreprintCancer Biology