Author

Jesse Stone Handler

Emory UniversityORCID 0000-0001-5444-3905Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Elana Judith FertigiD· 1 shared Gregory B. LesinskiiD· 1 shared Hani GoodarziiD· 1 shared Hongyu Huang· 1 shared James E. Forsmo· 1 shared Jessica LiniD· 1 shared Kawther AbdillehiD· 1 shared Margaret A HalliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Elana Judith FertigORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 17, 2026

MetScore and classical-basal subtype intersect to define chemotherapy response and tumor microenvironment architecture in pancreatic ductal adenocarcinoma

Raymond E. Preston, Hongyu Huang, Margaret A Hall…·Jesse Stone Handler

The paper integrates MetScore with classical-basal subtype to better explain PDAC metastasis, prognosis, treatment response, and tumor microenvironment than a single-axis model.

DOI 10.64898/2026.09.14.751470

humanbulk RNA-seq

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Cancer BiologyCell ReportsPeer-reviewedDec 1, 2025

Identifying a gene signature of metastatic potential by linking pre-metastatic state to ultimate metastatic fate

Jesse Stone Handler, Zijie Li, Rachel K. Dveirin…·Reza Kalhor

This study identifies a gene signature of metastatic potential by linking pre-metastatic states to metastatic outcomes in mouse pancreatic cancer and validates its relevance in human tumors.

3 citations

mouseATAC-seq

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