CK2 directly controls CARD9 protein homeostasis
Aya M. Kelly, Leidy C. Merselis, Benjamin Causton, Olivia K. Calder, Hoson Chao, Margaret M. Prack, Laurel B. Stine, Yuka Amako, Tao Wang, Ali E. Yesilkanal, Kendall J. Condon, Meekyum O. Pierce, Scott H. Watterson, Jason M. Guernon, Amit Anand, , Stephen C. Wilson
This study identifies CK2 as a regulator of CARD9 protein stability, showing CK2 inhibition leads to CARD9 depletion and demonstrating therapeutic potential in vivo.
ACS Chemical Biology · May 16, 2026Peer-reviewedImmunology